Not much to report today on the anti-aging project, all requirements being met, pills, stretching, HBOT, etc.
I wanted to talk about Fisetin today since I’ve found some new data. I take a massive dose (3500 mg) once per week with wine (because it is more bioavailable with ethanol) and will continue through the rest of the project and then stop for a while. I’m actually overdoing it, since the recommendation is a dose on two consecutive days for two consecutive weeks (total 4 doses). It is not something you take daily.
Fisetin has been proven to encourage non-functioning senescent cells to die and flush from the system. It has been shown in mice studies to extend life by 20% or so. Since senescent cells do not reproduce, you only have to do this occasionally, I’m thinking every six months. The science in this aspect appears to be good.
I’ve come across this article from Selfhacked that I wanted to comment on. This is apparently written by two pharmacists.
https://selfhacked.com/blog/15-science-based-health-benefits-fisetin-1-favorite/
It touts Fisetin as having beneficial effects on Diabetes, cancer, brain health, depression, Alzheimer’s disease and a whole lot of other health issues. One would think this is a miracle cure.
Frankly, I’m not buying it. Most of the claims and the references have little evidence behind them, and often only hearsay or theoretical benefits. The references are there, but I would expect a bit more discretion from professional pharmacists.
And this is what is wrong in the anti-aging field. There are so many supplements and so little actual field testing, so little scientific testing. While I believe Fisetin is useful in the way that I am using it, and have the studies to back them up to the degree that I need it. I would never recommend it to my friends or my audience for anything else. This appears to be more a sales pitch than an informative
This is why I’m doing the Tim vs. Aging Project — to test on myself and bring you the result (or the non-results), hopefully with objective data. The lesson is that if it is too good to be true, at least examine the research behind it.
Tim vs. Aging – T minus 8 days – Choosing the Epigenetic Test
Tim vs. Aging – T minus 4 days – Stretching and Weightlifting
Tim vs Aging – Day 8 – Anyone want to knock 20 years off of their biological age?
Tim vs Aging – Day 11 – Some Baseline Data, and Maintaining Consistency
Tim vs Aging – Day 12 – Over the First Hump, plus Do Bodybuilders Die Sooner?
Tim vs Aging – Day 13 – Fasting Day, Ketosis Explained, plus What the Heck is a Niacin Flush?
Tim vs Aging – Day 17 – No Weight Soreness, Gotta Have Pudding! – Develop Your Support System
Tim vs Aging – Day 18 – Torture by Trisha, Support Systems (cont.)
Tim vs Aging – Day 19 – Fasting Day, and Bacteria to Lose Weight
Tim vs Aging – Day 20 – Torture, but not too bad – plus a Cult progeny that is Good For You!
Tim vs Aging – Day 21 – Travel Day Screws the Schedule. And I am Officially Young Again!!!
Tim vs Aging – Day 22 – Still Traveling. Let’s talk about ‘Caloric Restriction’
Tim vs Aging – Day 23 – Travel Second Day – Plus Transhumans and Cutting Edge Biotech
Tim vs Aging – Day 24 -Travel Third Day – plus Potential for Brain Cell Repair
Tim vs Aging – Day 25 – Homebound – Makeup for lost time – lost weight – Oysters!!
Tim vs Aging – Day 26 – MMA workout – plus Hair Color Restoration?
Tim vs Aging – Day 27 – A Bit Sore – plus Criticism of the Hyberbaric Chamber Strategy
Tim vs Aging – Day 28 – Fasting – plus Will Immortality Lead to Overpopulation?
Tim vs Aging – Day 29 – Fasting is easy – plus Why Don’t People Exercise???
Tim vs Aging – Day 30 – Half Way There! Some Subjective Results
Tim vs Aging – Day 31 – Minor Schedule Break – plus Extending Life with Stem Cells
Tim vs Aging – Day 32 – All is Normal – plus Fish Oil, good or not?
Tim vs Aging – Day 33 – Feeling my Oats! Relief from Muscle Pain, Disappointed in Tae Kwon Do
Tim vs Aging – Day 34 – On Track – Plus my Theory on Foot Massages
Tim vs Aging – Day 35 – Fasting, a Shot in the Arm, Plus Creatine
Tim vs Aging – Day 36 – Trisha Rained Out – Plus Human Growth Hormone (HGH)
Tim vs Aging – Day 37 – Saturday Downtime, Plus Do Eating Right and Exercise Help? Maybe Not…
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