Long Life and Health
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Aging Health

New Study on the Antiaging Benefits of NAD

In the last few years, NAD+ has been making quite a splash with the antiaging community and has become one of the most popular supplements to include in an antiaging regimen. Nicotinamide Adenine Dinucleotide (NAD+) is found in nearly all our living cells. NAD is essential for sustaining life.  

NAD+ is a coenzyme essential for life. Next to water, NAD+ is the most abundant molecule in the body. NAD+ facilitates all of the processes that allow your cells to produce the energy you need to survive. Without NAD+, you would quickly die. In fact, modern aging research has discovered that the level of NAD+ in your body steadily decreases as you age. By the time we are 50 years old, for most of us, our NAD+ levels are about half of what they were when we were 20.

This has prompted a wealth of research into the idea that supplementing with NAD+ and/or its biological precursor NMN (Nicotinamide mononucleotide) can improve health and possibly even improve longevity. A recent study has found that NMN, a necessary precursor to the natural production of NAD+, does indeed “ameliorate” some of the health issues associated with “aging” in mice.

Key Takeaways From This Study:

  • NAD+ availability decreases with age and in certain disease conditions
  • Nicotinamide mononucleotide (NMN), a key NAD+ intermediate, has been shown to enhance NAD+ biosynthesis and ameliorate various pathologies in mouse disease models.
  • NMN suppressed age-associated body weight gain, enhanced energy metabolism, promoted physical activity, improved insulin sensitivity and plasma lipid profile, and ameliorated eye function and other pathophysiologies related to aging.
  • NMN effectively mitigates age-associated physiological decline in mice. Without any obvious toxicity or deleterious effects.
  • These effects of NMN highlight the preventive and therapeutic potential of NAD+ intermediates as effective antiaging interventions in humans.

You can read the complete study entitled, Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice, by clicking on the link.

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