Aging gracefully is no longer just about good genes or skincare and exercise routines. Nutritional supplements can help, but which ones really work? Many so-called “antiaging” products make dubious claims about making you look and feel younger, yet few are supported by any real evidence. Today, we present five science-backed supplements that are emerging as powerful tools to slow down cellular aging, support energy production, and help the body store energy more efficiently as we age.
A Harvard-trained physician, Dr. Josh Helman, has recently identified these five supplements that may contribute to healthy aging. Each works in a unique way, targeting inflammation, circulation, muscle strength, and cellular repair.
- Honokiol
Honokiol is a plant extract that was purified from the bark of the magnolia tree and has been used for millennia in traditional Asian medicine. Studies indicate Honokiol can lower inflammation and oxidative stress—two highly active processes in aging. It also has neuroprotective properties, maintaining brain function and cell resistance.
- Creatine
Creatine is naturally present in the body and is held in muscle tissue, where it makes quick energy production possible. It’s already familiar to many athletes, but recent evidence indicates that it’s useful for the elderly as well. Creatine preserves muscle strength, power, and mobility, functions that are lost with time.
- Nitric Oxide (NO) Boosters
Nitric oxide is a naturally occurring compound that causes blood vessels to relax and dilate, increasing circulation. Nitric oxide levels in the body decrease as we age. Having nitric oxide levels regulated will provide greater blood flow, cardiovascular health, and oxygenation to body tissues.
- PectaSol
PectaSol is a pure citrus pectin for increased absorption. It has been demonstrated to bind to a protein, galectin-3, which has been associated with inflammation, tissue damage, and premature aging. By cross-linking with galectin-3, PectaSol might potentially assist immune balance, detoxification, and cellular health.
- NMN (Nicotinamide Mononucleotide)
NMN is a compound that assists the body in producing NAD+, a coenzyme critical in energy metabolism, DNA repair, and cell renewal. NAD+ depletes as age progresses, and supplementation with it may be capable of maintaining cellular function in the youthful state. Animal and early human research indicate that NMN could enhance muscle strength, metabolism, and energy efficiency. It could also maintain cardiovascular function and lifespan by repairing cellular energy systems
While none of them are miracle cures, there is clinical evidence to support their antiaging effects. Together with diet and exercise, they offer a more holistic and science-based approach to longevity and aging well.