Long Life and Health
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Aging

Thirteen-Year Antiaging Study Concludes With Astounding Results

A thirteen-year research study into practical methodologies for antiaging and extending the human lifespan has concluded and provides some astonishing results.

The report is based on the work of renowned antiaging researcher David Sinclair.

Conventional wisdom among scientists for years has been that DNA mutations over time cause aging. However, a team of scientists led by Harvard Medical School professor David Sinclair appears to have shown that epigenetic changes (chemical and structural changes that affect genes, but without DNA sequence alterations) could instead be an important — and perhaps even the primary — cause of aging.

The report goes on to state, “Sinclair and his fellow researchers published results on Jan. 12, 2023, in the scientific journal Cell detailing their findings from a 13-year study. His previous research had shown that epigenetic changes coincide with aging. However, last week’s report demonstrated that these epigenetic changes actually drive aging.”

 

Over the course of the 13-year probe, experimentation began with mice to induce aging by mimicking breaks in chromosomes that didn’t alter their genetic code. Subsequent gene therapies were able to reverse the aging; further experimentation will begin soon on monkeys and, if successful, humans.

Should these results continue, however, as promising as they appear to be, Sinclair and his team report that “it could be decades” before procedures would be available to be prescribed for human treatment.

 

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